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531 đź’Ľ AbbVie Science Jobs / Employment

Senior Scientist I, Immuno-Oncology

new2 minutes ago
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We seek a highly motivated scientist with a proven track record of accomplishment in the field of immunology/oncology to join a team dedicated to the identification and validation of novel targets for cancer therapy. The incumbent will be responsible for driving innovation and executing a range of cytometric techniques including high-dimensional immunophenotyping and cell sorting, to support multiple immuno-oncology projects throughout AbbVie oncology. The successful candidate will also be responsible for conducting independent research to identify and validate novel immune-oncology targets utilizing a variety of cell biology, biochemical and genetic approaches. Applicants should have extensive laboratory research experience and a desire to continue in a laboratory-focused role. The individual must have demonstrated expertise in the theory and application of flow cytometry and be able to master a variety of instrument platforms and associated software, both at the level of data acquisition and post-acquisition analysis. In addition, this individual should have a solid working knowledge of innate and adaptive immune cell biology and tumor/immune cell interactions. Strong communication and teamwork skills are essential as the candidate is expected to operate in a fast-pace multi-disciplinary environment, interacting with diverse groups of experts within or outside of his/her scientific discipline. The position grade level will be filled commensurate with experience. Basic: BS, MS, or Ph.D. in Immunology, Cell/Molecular Biology, Cancer Biology, or related field 10 years (BS), 8 years (MS), or 0 (PhD) years post-graduate experience in cancer immuno-oncology, Demonstrated expertise in high dimensional cytometry and knowledge of cutting-edge analysis techniques is highly preferred. Record of scientific achievement (i.e.strong publication and/or patent record) and proficiency in standard biochemical, cellular and molecular techniques. Ability to thrive in a collaborative, matrix-based team environment and strong written and oral communication skills are essential. Previous experience in pharmaceutical drug discovery is preferred but not required. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance Learns fast, grasps the \"essence\" and can change course quickly where indicated Raises the bar and is never satisfied with the status quo Creates a learning environment, open to suggestions and experimentation for improvement Embraces the ideas of others, nurtures innovation and manages innovation to reality AbbVie is at the forefront of cancer research, discovering and developing novel treatments to address unmet medical need for cancer patients. Our strong pipeline includes both small molecule and biologic therapeutic approaches with first in class agents that target angiogenesis, metastasis, signal transduction, resistance to apoptosis and other cancer hallmark pathways. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: ancmg, aoa, cancer, hem onc, hematology, lah, oncology, palliative, physician md, physician md do

Manager, Environmental Health and Safety (EHS)

newabout 1 hour ago
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This position will develop, implement and maintain global EHS programs and provide technical expertise to AbbVie's global organization within the scope of responsibility. Key Responsibilities Include: Develop and maintain EHS Global standards, policies, systems and programs applicable to area of responsibility Provide EHS leadership and direction for management, professional, technical and support staff in area of responsibility Ensure systems are in place to enable area of responsibility to operate in legal and ethical compliance with regard to EHS issues. Provide business perspective, strategic and tactical direction to develop and implement EHS initiatives for the EHS Long range plan Authority to represent AbbVie externally on matters related to EHS with external regulatory agencies and non-government organizations Maintain a broad understanding of local, regional and global EHS regulations and practices for area of responsibility Maintain and update IT reporting databases and generate monthly and quarterly EHS performance reports to area management. Bachelor's Degree (EHS related, Engineering) plus 5 - 12 years of EHS related experience or Master's Degree (EHS related, Engineering) plus 5 - 10 years of EHS related experience. EHS related experience in manufacturing or R&D environments are required. Experience in a chemical plant operations or Oil and Gas environments is preferred, but not required. EHS or Engineering professional certification is preferred, but not required. Working experience in implementing EHS regulations, conducting incident investigations, interacting with regulatory agencies and external organizations and managing cross functional teams Development of practical, applicable standards and/or policies that meet business objectives. Technical expertise in the EHS functions as well as technical writing and business communications. Ability to actively listen, build and maintain effective working relationships with internal/ external colleagues and stakeholders, and resolve conflict Ability to successfully manage project and programs. Key Stakeholders: Patients, Company employees, direct reports, company management, cross functional teams, global regulatory authorities and external organizations. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: climate, environment, health, health and safety, osha, recycle, recycling, safety, safety specialist, sewage

Scientist I, Assay Development (ADC Discovery)

newabout 2 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica, Venclexta, and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position is based at Stemcentrx, AbbVie's South San Francisco, CA location. As part of a talented and multi-disciplinary team advancing exciting new approaches to drug discovery and development, AbbVie Stemcentrx is looking for a highly motivated scientist with experience in small molecule and ADC screening. The successful candidate will drive discovery work to understand small molecule potency and how it relates to ADCs. Primary responsibilities will include generation and review of small molecule cytotoxicity and mechanistic data. This position will also contribute to other target and ADC validation activities. RESPONSIBILITIES: Support small molecule screening efforts by independently performing assays to evaluate potency of compounds with diverse mechanisms of action Support efforts to understand potency and mechanism of action of novel small molecules used as warheads on antibody drug conjugates Plan and execute in vitro targeted drug combination studies Implement liquid handling automation into current workflows Work cooperatively with multidisciplinary teams and present results at team meetings Proactively seek out and incorporate novel ideas in line with the group's strategy to better characterize our antibody targets, toxins and ADCs Participate in the drafting of IND and patent documents MS or equivalent education with 3 years of relevant experience, or BS or equivalent education with 5-6 years of relevant experience. Experience in assay development, cell biological assays and small molecule screening is required Experience with liquid handling automation, cell imaging systems and flow cytometry highly preferred Prior experience with ADCs and working knowledge of bio-conjugation chemistry a plus. Excellent oral and written communication skills and a proven track record of working effectively in a dynamic, collaborative, team-oriented setting. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: aseptic, aseptic technique, drug discovery, food, health, injury, metabolism, nutritionist, patient, toxicologist

Associate Scientist/ Scientist, Proteostasis Biology in Neurodegeneration

newabout 4 hours ago
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We are seeking a cell/molecular biologist, preferably with pharma/biotech background, to join the proteostasis group at the Foundational Neuroscience Center (FNC) in Cambridge, Boston . This individual, with a background in cell biology and/or neuroscience and strong technical expertise in molecular and cell biology, will be responsible for supporting early drug discovery efforts to identify and validate novel drug targets. This individual should enjoy working with novel technologies and thrive in a small biotech atmosphere with the resources of a large pharmaceutical company. This individual's responsibilities will also include assay development and validation, as well as characterization of model systems to study proteostasis biology and its contribution to neurodegenerative disease. Key Responsibilities: Contribute technical and scientific expertise to proteostasis project teams Execute on a planned experimental design - collect, analyze, interpret and present data Generate robust and complete data sets to support key Go/NoGo decisions on novel drug targets Develop expertise with novel technologies and laboratory techniques Lead and/or assist in writing and revising SOPs Work diligently and efficiently to meet deadlines in a fast-paced environment Read and apply relevant scientific literature Adhere to safety and compliance Participate and present in internal meetings Position will be hired based on level of experience. BS or MS in biology or related field with 3-5 years (BS), or 0-2 years (MS) of pharmaceutical and/or biotech industry experience Proficiency with cell culture techniques, transfection and lentiviral transduction methods Experience working with iPSC-derived neurons and/or primary rodent neurons. Proficiency with cellular analytical techniques such as immunofluorescence microscopy, high-content imaging, and flow cytometry. Skilled with basic laboratory techniques such as ELISA, western blotting, luminescence assays, FRET/fluorescence assays, and qPCR. Aptitude for basic statistics and software packages such as GraphPad PRISM Demonstrated ability to work well in a collaborative team-oriented environment Demonstrated ability to learn, understand and master new experimental techniques Strong organizational skills that enable multitasking and working within timelines Demonstrated record keeping, scientific writing skills, and strong verbal communication skills Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: bio, bioengineering, biology, biomaterials, bioprocess, genetic, neuro, nutrition, pathogenesis, therapeutic

Associate Director, External Collaborations

newabout 5 hours ago
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Purpose:Describe the primary goals, objectives or functions or outputs of this position.Advance the Oncology pipeline by identifying potential combinations of AbbVie late-stage assets with emerging (and anticipated) standard of care and partner with TLC to execute select collaborations. Serve as the lead for the matrix organization comprised of internal stakeholders (CST, Translational Biology, TLC, Legal, Medical Affairs, and others) to understand business needs and develop strategy framework. Support certain transactional aspects of partnership agreements by working closely and effectively with TLC, primarily on protocols and budgets.Responsibilities:Work with CST lead (or designate) and post-POC Translational Biology team to identify program development gaps, map out partnering options for a specific asset, and present recommendations.Together with TLC and Legal, develop a coherent and effective contracting strategy in order to implement TA partnering recommendationsServe as primary point of contact for clinical protocols and other scientific discussions with partnersCoordinate assessment of the external asset and the available scientific information (e.g., pre-clinical data, investigator's brochure, etc.) with CST, Safety, etc. and put forward preliminary development plan.Work with TLC to coordinate necessary discussions with external partners to address study design and conduct, and other relevant questions.Develop a project tracking tool and provide regular and timely updates to TA.Together with CST and Clinical Operations team develop required budget.Support TLC and Legal, as requested, in review of term sheets and/or major terms and developing negotiation strategies.Following contract execution, support study/protocol related interactions with collaboration partner.(if not supported by Alliance Management). Keep TLC abreast of any alliance issues and bring contractual considerations to TLC as they arise.Support strategic academic collaborations (research proposal review and funding, annual scientific symposia, quarterly clinical spend reports).. Bachelor's degree in the sciences; advanced degree (e.g., MS, PhD) preferred.10 years of pharmaceutical industry experience with at least 3 years of clinical trial experience in the pharmaceutical industry, academia, or equivalent.Ability to interact externally and internally to support a global clinical and partnering strategy.Ability to provide input and direction to internal stakeholders with appropriate supervision.Strong desire to collaborate in a cross-functional setting with ability to perform and bring out the best in others.Knowledge of clinical trial methodology, and experience in development of clinical strategy and the design of study protocolsMust possess excellent oral and written English communication skills.Proven track record of developing and implementing complex processes and high impact projects.Ability to effectively communicate key information to senior management.Ability to appropriately and effectively use resources to complete tasks and meet required timelines.. At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic. Associated topics: administrative, administrative assistant, administrative officer, administrative staff, assistant, document, front desk, operational assistant, records management, staff

Senior Scientist II, Protein Analytical Chemistry, CMC Biologics

newabout 7 hours ago
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AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world's most complex and critical conditions. The company's mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world. DESCRIPTION: Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica , Venclexta , and Empliciti and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus' and CAR-T cells. POSITION DESCRIPTION We have an exciting opportunity for a Senior Scientist to join the Protein Analytical Chemistry Group (within CMC Development) at the AbbVie location in Redwood City, CA. AbbVie Redwood City is an R&D organization focused on development of innovative biologics in the field of Oncology. In this role, you will utilize your knowledge of analytical protein chemistry and expertise in chromatography and capillary electrophoresis to contribute to CMC development of AbbVie's growing pipeline of clinical stage oncology biotherapeutics, which include novel bispecific constructs, antibody-drug conjugates, and monoclonal antibodies. Key Responsibilities Include: Independently develop and apply state of the art capillary electrophoresis and HPLC methods to characterize biotherapeutic proteins and their associated variants and impurities. Identify post-translational modifications and characterize structure-activity relationships of products under development. Develop innovative approaches to solve difficult analytical challenges. Represent the Protein Analytical Chemistry Group as a subject matter expert on cross functional project teams. Develop, qualify/validate, and transfer fit-for-purpose QC release and stability methods. Provide technical support and oversight for QC testing occurring at internal and external GMP laboratories. Plan and author characterization, comparability, and quality sections of regulatory submissions (INDs/CTDs). Engage and influence the broader scientific community through publications and poster and oral presentations at industry conferences. Ph.D. in Chemistry, Biochemistry, or related field with 4 years of relevant industry experience (or comparable combination of degree and experience) for Senior Scientist II. Position may be a lower level based on degree and total years of relevant experience in industry and academia. Must possess a solid understanding of protein chemistry and biochemistry, particularly as related to biotherapeutic protein drug development. Experience representing analytical development function on cross-functional project teams. Experience planning and coordinating analytical development projects involving multiple contributors and stakeholders is required. Demonstrated proficiency in developing and performing capillary electrophoresis and HPLC methods as they apply to protein characterization. Experience with CMC analytical development of monoclonal antibodies or related biotherapeutic proteins is required. Proven record of advanced technical/scientific achievement and innovation. Quality control and/or GMP experience is beneficial. Must have strong written and verbal communications skills. Must be capable of working in a fast-paced, collaborative environment and managing multiple concurrent projects with a high degree of independence. **Equal Opportunity Employer Minorities/Women/Veterans/Disabled** Associated topics: bacteria, bio, biology, biostatistics, immunobioengineering, microbiology, pathophysiology, physiology, protein, stem cell

Associate Director, Emerging Channel Insights - Payor and Policy

newabout 7 hours ago
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The Sr. Manager of the Emerging Channel Insights team, will play an important new role in AbbVie's Market Analytics and Business Insights Team supporting the evolving Market Access organization. The team will be focused on providing insights and analytics into 1) engagement strategies with emerging economic decision makers such as Employers, Benefit Consultants and Organized Providers, and 2) understanding impacts of Private/Govt. healthcare policies and emerging portfolio-wide events/ issues in the Market Access landscape (i.e. growing 340B, Accumulator/ Maximizer, etc...) across multiple therapeutic and customer segments . This individual will closely collaborate with internal Market Access Marketing stakeholders from Health Systems/Employers, Payor Channel, Policy teams; Field Based Account Executives within the Hospital Systems teams; and leaders within Government/Public Affairs, Legal, Finance, Pricing, HEOR, and Medical Affairs. The remit of the individual will be to influence AbbVie strategies and policies through insights, including the assessment of strategic and financial implications of market dynamics related to both existing and proposed policy proposals. With a focus on these Emerging Stakeholders, this role will help to inform and influence AbbVie U.S. Commercial toward having an appropriate strategies and capabilities in place for our current products, as well as future pipeline products. Key Responsibilities Include: The Sr. Manager is for research and analytics addressing high urgency portfolio-wide issues that inform AbbVie's strategies and policy positions. Key areas of functional scope include: Leading the insights (primary research & analytics) deliverable for portfolio-wide issues and market trends for emerging stakeholders and anticipating their needs. Provide a perspective current market events, healthcare policy changes and implications to AbbVie U.S. portfolio and strategy. Conducting primary research to understand needs of stakeholders such as Health Systems, Employers, Benefit Consultants and Advocacy Groups. Address the impact of high urgency, portfolio-wide issues and/or initiatives such as 340B, Accumulators, benefit design changes, Medicare Part D program design, CMS policy changes. Support \"Above Brand\" initiatives such as Stakeholder Segmentations, Follow the Money mappings, capability building, etc...that require a high level of experience, project management and organizational influencing skills. Supervisory / Management Responsibilities Exempt Direct Reports: none Education Required: Bachelor's degree in one of the following fields: Market Research, Statistics, Economics, Actuarial Science, Decision Sciences, Operations Research, Engineering, or Applied Mathematics; MBA Preferred, Background/Desired Skill Set The Emerging Channel Insights leader should have the following background: Working knowledge of multivariate statistics, analytical software and pharmaceutical data sources (IQVIA, Symphony Health, IHS, MMIT/ Fingertip Formulary/Business One Technologies, HIRC, etc....). Minimum of 8 years of experience in market analytics, and field sales support in the pharmaceutical or related industry Minimum of 4 years of experience in market access with significant subject matter expertise with Health Plans, PBMs, Hospital Systems, Specialty Pharmacies and Healthcare Policy. . Strong story telling skills; ability to distill complex information synthesized into concise and impactful messages and communications. Demonstrate strong team collaboration with business stakeholders and Commercial Analytics and Operations partners. Position will be filled as a grade 19 or 20, based on candidate experience. Associated topics: advertise, alumni, demand, facebook, market, mba, presale, public relations, regulatory, stewardship

Senior Scientist III, NCE Analytical Chemist

newabout 9 hours ago
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The New Chemical Entity Drug Product Development Analytical Group is responsible for developing and validating analytical methodologies for both active pharmaceutical ingredient (API) and drug product to enable clinical trials, toxicology studies and drug product development for Abbvie's pre-clinical and clinical candidates. We are responsible for Chemistry Manufacturing Controls (CMC) support from first in human trials through NDA/MAA application. Our laboratories operate under both Good Laboratory Practices (GLP) as well as Good Manufacturing Practices (GMP) to enable release of materials for pre-clinical and clinical studies respectively. AbbVie is seeking a Senior Scientist III, Analytical Chemistry to conduct analytical research and development in support of pre-phase I development to market authorization. Key Responsibilities Include: Responsible for method development, testing procedures, and implementation of analytical controls to help the advancement of new molecular entities (NME's). Leading the analytical aspects of a project while jointly working with other functional areas to advance NME's through the pipeline. Identifying talent and developing leadership capabilities in the broader scientific staff of the department. Implement a wide range of current analytical techniques to conduct research and development studies related to drug product development Support new product development with advanced methods development and validations, technical transfer packages, and generation of technical data and reports in support of clinical NME regulatory requirements in a cGMP environment. Conduct research in the area of analytical technologies with pharmaceutical applications. *Level and compensation will be commensurate with experience. Basic: Ph.D. in Analytical Chemistry/Organic Chemistry or other relevant discipline with a minimum of 6 years of relevant experience. Proficiency with analytical techniques including-HPLC, GC, spectroscopic techniques, and mass spectrometry, especially as they relate to pharmaceutical quality. Candidate must possess a solid fundamental background in separation theory. This position requires an individual who is self-motivated, hard-working, detail-oriented and able to work in a fast-paced team environment with demonstrated problem solving skills. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the \"essence\" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: biochemistry, ceramic, coating, formulation, glass, latex, material, material science, polyurethane, rubber

Senior Scientist II/III, Pharmacology

newabout 9 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica, Venclexta, and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position will be based at Stemcentrx, AbbVie's South San Francisco, CA location. Description The Research Pharmacology Department is searching for a Senior Scientist II/III who will work collaboratively across DMPK, project-based teams, and biological discovery teams to formulate the in vivo efficacy strategy for various oncology programs, involving antibody drug conjugate and immunotherapy approaches. The candidate will be expected to develop strategies that combine their scientific expertise with in vivo oncology models with operations and resource utilization for projects at various stages. Additionally, the candidate will be responsible to create scientific questions, and coordinate efficacy analyses for communication to other teams via presentations and/or reports. The ability to work independently and efficiently on multiple responsibilities, and effectively participate and communicate as part of team, is a prerequisite. Key Responsibilities: Lead oncology mouse model establishment and coordination for efficacy and imaging studies Prepare and/or coordinate with team members to review and present/report analyses of efficacy studies for various projects across entire pipeline Contribute Pharmacology knowledge (including pharmacokinetics, pharmacodynamics) and strategy within project team structure Work across discovery teams to integrate efficient workflows for cross-functional analyses and endpoints (for example, biomarkers) Challenge the status-quo and contribute improvements to existing Pharmacology workflows, data visualization tools, efficacy operations, and strategies Job Requirements: PhD in Molecular & Cell Biology, or a related discipline, with 3 years of relevant research experience, preferably in a Pharmaceutical or Biotechnology industry setting Hands-on experience with strategy development and detailed design including benchmarks of in vivo efficacy studies Extensive knowledge of oncology models, including patient-derived and cell line-derived xenograft models, and genetically engineered mouse models Experience with pharmacodynamics endpoints, such as biomarkers or in vivo imaging, is a plus Strong written and verbal communication skills Scientific leadership abilities and collaborative personality Character Requirements: Flexibility and motivation to learn techniques and accomplish goals outside those stated above Ability to manage multiple responsibilities and meet deadlines in a fast-paced environment Entrepreneurial personality, with problem solving skills, critical thinking ability, and excellent communication skills Highly motivated and independent with an ability to adapt to changing priorities in a fast-paced environment Raises the bar and is never satisfied with the status quo Excited to participate in and contribute to company culture At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic. Associated topics: antibody, disease, food, food scientist, microbiology, nutritionist, pharmacometrics, physiology, transfection, virus

Senior Scientist I/II, Immuno-Oncology - Redwood City

newabout 10 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica , Venclexta , and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position will be based at AbbVie Biotherapeutics (ABR), AbbVie's Center of Innovation in Oncology Research and Development, located in Redwood City, CA. ABR R&D efforts focus on two key areas: Immuno-Oncology (I-O): developing therapeutics that activate the immune system to recognize and eliminate cancer cells Antibody drug conjugates (ADCs); antibodies conjugated to potent toxins for directed delivery to cancerous cells while sparing healthy tissues. ABR employs approximately 160 individuals in the San Francisco Bay Area. Its size and entrepreneurial work force allows for effective cross-functional collaboration, agility, and rapid decision making. We are seeking a highly motivated individual to join AbbVie's rapidly expanding Immuno-Oncology group. The successful candidate will have expertise in T cell biology as well as cellular-based/chimeric T cell receptor-based therapeutics. This individual should have deep technical experience in immunology and oncology research with preferred experience in T cell biology including T cell receptors and peptide MHC antigens. This individual will be responsible for generating antigen-specific T cell clones, identifying and characterizing T cell receptors and engineering soluble T cell receptor-based therapeutics. This person will ensure scientific excellence, quality and completeness of key platform initiatives. The successful candidate will collaborate in a multidisciplinary research team in an exciting, fast-paced discovery-oriented environment. Ph.D. in Immunology or related major with typically 0-4 years (Senior Scientist I) or 4 years (Senior Scientist II) of experience. Preference for some industry experience Demonstrated excellence and productivity in independent research. Extensive knowledge of T cell biology research. Excellent written and verbal communication skills are essential. Level commensurate with experience Practical experience in primary cell culture, T cell based assays, and with molecular biology techniques is required. Skills include, but not limited to: flow cytometry (FACs), PCR, qPCR, ELISA, Luminex, retroviral/lentiviral based transduction systems, T cell clone generation. Highly developed written and communication skills, and the ability to work in a highly collaborative team setting is essential. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: ancmg, aoa, cancer, hem onc, hematology, lah, oncology, physician md, physician md do, thedacare

Senior Director, Corporate Strategy Group - AbbVie

newabout 11 hours ago
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T he Senior Director, Decision Support Group (DSG) is responsible for leading all decision analysis projects in one key area of DSG (e.g. Portfolio Analysis; Asset Analysis) and/or a business group. The position is responsible for all productivity and quality of the DSG interactions and project or portfolio output. The Senior Director, Decision Support Group reports to the VP of Portfolio Analysis and Assessment and will manage a team. Key Responsibilities Include: Leads decision projects of the highest strategic importance. Has primary responsibility for all projects in primary area of responsibility. Sets project priorities and assignments. Has personnel and budgetary responsibility. Oversight of project quality and output. Basic: Ph.D. in physical or Decision Sciences, or MBA, 10 years of decision analysis or similar experience in relevant field. Experience in conducting multiple decision analysis and portfolio analysis projects. Ability to select and apply the appropriate decision analysis methodology and techniques to non-standard / non-typical problems presented to DSG. Proven track record of facilitating delivery of high quality and insightful decision analyses. Leadership experience in any of the areas of pharmaceutical R&D, marketing, or commercialization. Proven management experience. Preferred Experience: Strong organizational and project management skills commensurate with conducting multiple decision analysis projects and/or highly sophisticated projects. Broad strategic perspective across all aspects of pharmaceutical R&D and commercial areas. At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic. Associated topics: b2e, channel partner, franchise, franchise owner, franchise operator, guest, inside sales, mba, regional sales, retail

Senior Scientist I/II, In Vivo Pharmacology, Parkinson's Disease

newabout 11 hours ago
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AbbVie is investing heavily in a new research enterprise in Cambridge, Boston - the Foundational Neuroscience Center (FNC). The FNC will investigate the fundamental biological mechanisms underpinning neurodegenerative disease, especially Alzheimer's disease. AbbVie is seeking an experienced, highly motivated, lab-based Senior Scientist with experience working with biologics and small molecules in preclinical models of Parkinson's disease to join the FNC In Vivo Pharmacology team. The successful candidate will independently design and implement experiments to address target engagement, mechanisms-of-action and efficacy of therapeutic molecules. Key Responsibilities Includes: Design and interpret in vivo pharmacology studies to evaluate the activities of biologic drug candidates including PK/PD characteristics, target engagement, mechanisms of action and efficacy Collaborate with key internal and external scientists to drive improved understanding of disease pathophysiology and target biology Oversee interactions with contract research labs and academic institutions for preclinical studies, including lab selection, protocol development, oversight and review of final report Train and manage direct reports Position will be hired based on level of experience. PhD in Neuroscience or related field with 0-4 years of academic or industry research experience; MS with 8-10 years of experience; BS with 10-12 years of experience. Must have experience designing and conducting in vivo pharmacology studies with in animal models of Parkinson's disease Excellent in vivo skills (dosing, tissue/fluid harvest) and prior experience doing biochemical and/or histological analysis required Experience in standard molecular biology and protein biochemistry techniques (e.g. protein purification, ELISA, WB) is also highly preferred Outstanding organizational and critical thinking skills Excellent verbal and written communication and interpersonal skills to work across functions and across sites, and within academic collaborations Associated topics: antibody, bacteria, biopharma, dietary, kinesiology, metabolism, nephrology, nutritionist, pharmacology, trauma

Maintenance Technician III - Ops - AbbVie

newabout 11 hours ago
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To provide multi craft, skilled maintenance support to Abbvie Lake County Facility, Utility, Manufacturing, and R & D assets.Key Responsibilities Includes: Adhere to Abbvie's code of conduct and safety policies.Independently performs senior level maintenance work including but not limited to; machine lubrication, inspection, troubleshooting, repair, and fabrication.Works closely with Department Reliability Engineering regarding; Maintenance Program development, Root Cause Analysis (RCA), and

Sr. Medical Science Liaison - Dermatology Atlanta - AbbVie

newabout 11 hours ago
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External expert (opinion leader) cultivation: Identifies, gains access to, and develops professional relationships with external experts in therapeutic areas of interest within assigned geography. Provides education relative to disease state and AbbVie products across the product lifecycle to healthcare providers and researchers. Serves as a medical/scientific resource to healthcare providers through answering unsolicited medical questions, and addressing other clinically related medical information issues. Clinical trial support: Supports research initiatives across development at the request of R&D to include but not limited to, site evaluation and identification, recruitment, investigator meetings, external expert identification, and study management. Project management: Works with internal Medical Affairs customers to develop and execute a territory plan designed to support and meet shared business objectives. Inputs and maintains internal database as it relates to activities in their geography. Prepares marketplace in new therapeutic areas of interest, which includes creating awareness and relationships for AbbVie in the Medical community. Serves as a scientific resource to commercial partners, as appropriate, to support activities Self-development: Develops and communicates a professional growth plan. Continually educates self on global market issues, trends, and product knowledge as it pertains to specific business responsibilities in key therapeutic areas. Takes responsibility for and actively manages professional development. Advanced degree required (i.e. Pharm D, MD/DO, PhD, PA or NP, BSN) in a relevant scientific discipline. Doctorate strongly preferred in a health science or clinical discipline. Significant industry experience in relevant therapeutic area may be accepted in lieu of education requirements. Greater than or equal to 2 years as a Medical Science Liaison required. At least 3 years of clinical, scientific research or industry related experience or equivalent required. Previous pharmaceutical industry experience within relevant scientific discipline preferred. Ability to identify, analyze, and translate specific territory and corporate needs in order to support both internal and external customers and achieve business and clinical objectives. The Senior Medical Science Liaison must be able to identify, analyze, and translate specific territory and corporate needs in order to support both internal and external customers and achieve business and clinical objectives. An essential requirement of your position is to meet health care industry representative (HCIR) credentialing requirements to gain entry into facilities and organizations that are in your assigned territory. These HCIR credentialing requirements may include, but are not limited to, background checks, drug screens, and proof of immunization/vaccination for various diseases. At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic . Associated topics: bacteria, clinical, dietetic, immunohematology, injury, metabolism, patient, pharmacometrics, toxicologist, transfection

Postdoc - Postdoctoral Fellow Biomedical Imaging Analysis - North Chicago

newabout 12 hours ago
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The Postdoctoral Program is designed for true investigational and experimental research. Participants will be mentored by renowned industry scientists and collaborators at AbbVie and focused on delivering cutting-edge advancements in Discovery, Development Sciences and BioPharma. The enriching training program offers a balance of structured learning and work experience which fosters a learning environment to advance individual development with accessibility to high-level knowledge building across the drug development continuum. Technical expert that will investigate, identify, develop and optimize new methods/ techniques to address critical project needs. Continuously seek to improve existing laboratory methods and processes. Read and adapt literature to accomplish assignments. Demonstrate mastery of broad range of experimental techniques and methods of data analysis. Through our Postdoc program, we are hiring postdocs from key academic institutions for preferred areas of science in the U.S., while providing a unique opportunity for participants to build a solid career foundation in the pharmaceutical industry while building the AbbVie brand as an employer of choice for scientific talent. Participants in the Postdoc program play an integral part in our continued success and will help us to further grow as a leader in our industry. This assignment is expected to be for two years minimally and no more than three years. Project outline This project will focus on biomedical image analysis and modeling the progression of neurodegenerative diseases. The project will last for two years with the possibility of one year extension. The successful applicant will be based in AbbVie's Translational Imaging group, part of the department of Integrated Science and Technologies (iSAT). The Translational Imaging group, based in Lake County outside of Chicago, works across different disease areas (e.g. neurosciences, oncology, and immunology) applying biomedical imaging methods to accelerate drug development. The group is highly multidisciplinary including biologists, pharmacologists, chemists, physicists and mathematicians, and collaborates widely with other scientists and clinicians within AbbVie, leading academics and other industry groups. The accumulation of misfolded proteins, such as -amyloid, tau and -synuclein, is a feature of numerous neurodegenerative diseases including Alzheimer's Disease and Parkinson's Disease. Publically available databases from initiatives such as the Alzheimer's Disease Neuroimaging Initiative (ADNI) and Parkinson's Progression Markers Initiative (PPMI) have allowed the start of big data-like analyses in the neuroimaging field. The goal of this postdoctoral position is to utilize these (and other) databases to develop novel image analysis methods for monitoring and predicting the progression of neurodegenerative diseases. It is hoped that this project will result in novel and more sensitive outcome measures to evaluate spatiotemporal changes in protein aggregates, for application in clinical trials, and the development of methods to support patient stratification and clinical trial design. Abbvie is committed to publishing the results of this research. Key Responsibilities: Image processing and feature extraction from 4D imaging data reflecting the accumulation of misfolded proteins in neurodegenerative diseases. Develop and apply machine learning approaches to predict disease progression using multi-modal imaging and non-imaging biomarkers. Basic Qualifications: Successful completion of a PhD in Biomedical Engineering, Computer Science or a relevant discipline. Minimum graduate school GPA 3.0; 3.5 preferred. Graduate of accredited and nationally ranked university. Background in computer vision, image analysis, machine learning or neuroscience. Proficient in at least one of the following programming languages: Python, R, MATLAB, or C . Record of publication in a prestigious journal(s). Able to demonstrate the following skills/attributes: analytical thinking, critical thinking, collaboration, communication, partnership, and flexibility. Excellent problem-solving skills including critical and analytical thinking. Demonstrated ability to independently, interpret data, and identify appropriate follow-up strategies. Proven track record of teamwork, adaptability, innovation, initiative, and integrity. Global mindset to thrive in a diverse culture and environment. Work authorization in the United States. Preferred Qualifications: Experience with big data analytics and machine learning tools e.g. tensorflow, scikit learn. Experience with medical image analysis. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance Learns fast, grasps the \"essence\" and can change course quickly where indicated Raises the bar and is never satisfied with the status quo Creates a learning environment, open to suggestions and experimentation to drive the science in the field of interest Embraces the ideas of others, nurtures innovation and manages innovation to reality Apply: LINK For further information on the company and its people, portfolio and commitments, please visit www.abbvie.com . Follow @abbvie on Twitter or view careers on our Facebook or LinkedIn page. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: doctoral, drug discovery, fellowship, lab, laboratory, professor, research, research fellow, scientist, toxicologist

Scientist I/II, Histologist, Neuroscience - Cambridge

newabout 12 hours ago
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AbbVie is investing heavily in a new research enterprise in Cambridge, Boston - the Foundational Neuroscience Center (FNC). The FNC will investigate the fundamental biological mechanisms underpinning neurodegenerative disease, especially Alzheimer's disease.We are seeking an experienced, lab based Scientist with expertise in Histological analysis to join the In Vivo Pharmacology team at the FNC. This individual will be responsible for providing ex vivo support for variety of in vivo studies in animal models including target identification, target validation and efficacy for Alzheimer's disease and Parkinson's disease drug discovery projects. Key Responsibilities Includes: Working closely with team members to design and execute in vivo experiments with histological endpoints Developing new technologies and methods to understand disease pathophysiology and target biology Responsible for data collection, interpretation/analysis and presentation as needed Position will be hired based on level of experience. BS in biology or related field with 5-7 years of neuroscience-related experience or MS with 2-5 years of experience Experience doing histology, immunohistochemistry and image analysis required Experience doing paraffin histology (processing, embedding, sectioning) and/ or frozen (sliding microtome, cryostat) required Prior experience working with automated IHC/staining system (e.g. Leica BOND) preferred In vivo skills including animal handling, dosing and tissue collection preferred Outstanding organizational skills and excellent verbal/written communication skills required Associated topics: dietary, drug, drug development, health, histology, histotechnologist, immunohematology, microbiology, pharmaceutical, pharmacology

Scientist II/ Senior Scientist I, Virology - AbbVie

newabout 13 hours ago
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We are seeking a highly motivated and creative scientist with background in Virology, Immunology, and/or molecular biology to join the AbbVie Infectious Disease team in North Chicago, IL. We are looking for a Scientist / Sr. Scientist with experience in cell culture, tissue processing, flow cytometry (FACS), as well as standard molecular biology and biochemical techniques. Above all, we are looking for a highly motivated and collaborative individual with a passion for research, who enjoys working in a fast-paced and highly dynamic working environment.Key Responsibilities Includes: Perform mammalian cell culture and independently develop, run, analyze and troubleshoot in vitro assays, such as FACs & cell-based activity assays. Use developed in vitro assays to validate and characterize novel therapeutic entities. Demonstrate innovation and strong problem solving, analytical skills and be a team player. Work collaboratively with matrixed project teams and members of the group to drive innovation and deliver novel therapies for patients. Develop productive collaborations and communication with other groups across therapeutic areas. Timely documentation of experiments and activities in electronic archive systems. Engage colleagues in cross-disciplinary scientific discussion, present scientific data to the team. Basic: BS in Virology, Immunology, molecular biology, or related field with at 7 years of relevant experience or MS with 5 years of experience or a Ph.D with 0 years of experience. Extensive expertise in mammalian cell culture/transfection is required. Proficiency in a wide range of immunological laboratory techniques, in particular flow cytometric analysis (FACS). Proficiency in a wide range of molecular biology and immunology techniques (Molecular cloning, RNA isolation, c-DNA synthesis, qPCR, proliferation/cytotoxicity assays). Experienced in infectious disease research and BSL training or experience is a plus. Experienced in cell isolation and culture of primary immune cells (dendritic cells, macrophages and T cells) is a plus. Must possess the ability to design experiments and think independently. Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the \"essence\" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation an manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: antibody, biopharma, dietary, drug development, medical, medicine, nephrology, therapy, trauma, vaccine

Project Specialist, Sample Operations - Drug Metabolism and Pharmacokinetics, Bioanalysis

newabout 13 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica , Venclexta , and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position will be based at AbbVie Biotherapeutics (ABR), AbbVie's Center of Innovation in Oncology Research and Development, located in Redwood City, CA. ABR R&D efforts focus on two key areas: Immuno-Oncology (I-O): developing therapeutics that activate the immune system to recognize and eliminate cancer cells Antibody drug conjugates (ADCs); antibodies conjugated to potent toxins for directed delivery to cancerous cells while sparing healthy tissues. The Drug Metabolism and Pharmacokinetics Bioanalysis department at AbbVie Biotherapeutics Inc in Redwood City, CA is looking for a Project Specialist, Sample Operations . Key responsibilities include: Handles shipment, receipt, storage and transfer of biological samples in support of clinical and preclinical trials. Ensures end-to-end chain of custody documentation. Responsible for study setup in the bioanalytical research LIMS software based on defined timelines and standards. Ensures the correct storage and tracking of the biological samples in LIMS. Maintains knowledge of current regulations related to the sample handling and ensures that reconciliation is achieved to deliver assay-ready samples to testing teams. Ensure collection, delivery, analysis, and disposition of biological samples under the highest standards of quality, ethics, compliance, and in accordance with informed consent. Interacts closely with bioanalytical scientists, Laboratory Sample Operations Group, Clinical Sample Operations, and project team leads and/or therapeutic area liaisons with regard to sample chain of custody. Perform QC reviews of laboratory testing data and laboratory notebooks to ensure compliance with relevant guidelines and SOPs. B.S. or M.S. and at least 3 years relevant experience in bioanalytical areas required. Chemistry, biology and immunology background preferred. Expertise in LIMS Systems for sample handling and tracking storage preferred. Experience working under GLP/GCP regulation preferred. Ability to handle multiple tasks and detail oriented. Ability to prioritize and adapt to change. Very good organizational skills. Excellent interpersonal and communication skills, interfacing with departments and external partners Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the \"essence\" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic . Associated topics: manufacturing, medical technologist, meter reader, pharmacy technician, repair, service porter, service support, tech, technician laboratory, technician staff

Associate Director, Emerging Channel Insights - Trade

newabout 13 hours ago
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The Sr. Manager of the Trade & Distribution Insights team, will play an important new role in AbbVie's Market Analytics and Business Insights Team supporting the evolving Market Access organization. The team will be focused on providing insights and analytics into Trade & Distribution strategy, design & performance, respective Return on Investment across multiple therapeutic and customer segments. This individual will closely collaborate with internal Market Access Marketing stakeholders from Pharmacy/Trade Sakes and Marketing; leaders within Managed Care Brand Marketing, Legal, Finance, Pricing, and HEOR. The remit of the individual will be to influence strategy development through insights and evaluate performance of the Trade related contracts, program recommendation, and measure financial impact on AbbVie portfolio. With a focus on these Trade & Distribution Stakeholders, this role will help to inform and influence AbbVie U.S. Commercial toward having an appropriate strategies and capabilities in place for our current products, as well as future pipeline products. Key Responsibilities Includes:The Sr. Manager is responsible for research and data analysis that informs and advises AbbVie's Trade strategies: Leading the insights (primary research & analytics) development process required to support Distributor, Pharmacy and GPO strategy development. Leading on the development of data strategies for trading partners, including identifying analytical opportunities for value based engagements. Provide analytical leadership to the development and execution of a standardized performance measures and subsequent Return on Investment, and support Trade Quarterly Business Review initiatives. Evaluating the value of Specialty Pharmacy, Fee For Service (FFS) and Group Purchasing Organization (GPO) contracts for marketing and analyzing impact Informing financial projections by leading cross-functional meetings on post-deal account performance and variance. Supervisory / Management Responsibilities: Exempt Direct Reports: none Required: Bachelor's degree in one of the following fields: Market Research, Statistics, Economics, Actuarial Science, Decision Sciences, Operations Research, Engineering, or Applied Mathematics; MBA Preferred, Background/Desired Skill SetThe Sr. Manager should have the following background: Working knowledge of multivariate statistics, analytical software and pharmaceutical data sources (IQVIA, Symphony Health, IHS, MMIT/ Fingertip Formulary/Business One Technologies, HIRC, etc....). Minimum of 8 years of experience in market analytics, and field sales support in the pharmaceutical or related industry Minimum of 3 years of experience in market access with significant subject matter expertise with Distributors and Specialty Pharmacies. Strong story telling skills; ability to distill complex information synthesized into concise and impactful messages and communications. Demonstrate strong team collaboration with business stakeholders and Commercial Analytics and Operations partners. Position will be filled as a grade 19 or 20, based on candidate experience. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Travel: 20% Associated topics: chief financial officer, chief investment officer, controller, director finance, general manager, general operations manager, operation, president, senior director, staff

Senior Scientist, Biologics Discovery

newabout 14 hours ago
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Seeking a highly-motivated research scientist to join a dynamic core team supporting biologics drug-discovery. Key areas of focus would include an in-depth understanding of the relevance of glycans and glycan structure in biotherapeutic function as well as its role in major human diseases, with the aim of empowering biotherapies to increase therapeutic index, modulating glycan to effect therapy, or providing novel molecular targets. Candidate must have diverse therapeutic protein expertise and an understanding of how to both analyze and control post-translational modifications of biologic molecules. The candidate should have a demonstrated ability to independently develop and implement new technologies and platforms, and diverse experience in engineering of novel therapeutics, purification, and antibody-drug conjugation. Candidate should be a creative problem-solver capable of finding innovative solutions to challenges posed in developing next-generation novel biotherapeutics. Candidate should be capable of broader strategic thinking and participate in the identification, development, and implementation of new technologies/platforms that improve the efficiency of the overall drug-discovery process for therapeutic proteins, especially as related to the intersection of glycoscience and biotherapies. As part of Global Protein Sciences, the candidate will be working in a Discovery organization at AbbVie. She/he should be able to work independently while contributing in a team environment, and manage several projects simultaneously. Candidate needs to stay current with applicable internal/external scientific literature and apply new information in innovative ways to successfully complete work assignments. Should be able to analyze, document, and report data concisely and rigorously. Should possess excellent communication skills and be proficient in presenting in front of groups. Level and compensation will be commensurate with experience. Basic: Ph.D. in Biochemistry, Biophysics, Chemical Engineering or related field with 0 years experience. BS or MS in Biochemistry, Biophysics, Biochemical Engineering or related field with 10 (BS) or 8 (MS)years experience. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance Learns fast, grasps the \"essence\" and can change course quickly where indicated Raises the bar and is never satisfied with the status quo Creates a learning environment, open to suggestions and experimentation for improvement Embraces the ideas of others, nurtures innovation and manages innovation to reality Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: biochemistry, biosynthetic, fermentation, genetic, medical, neurodegenerative, neuroscience, pain, parenteral, pharmaceutical

Director, Pharmaceutical Development (API Pilot Plant Head) - North Chicago

newabout 14 hours ago
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Purpose: Lead the API Pilot Plant Organization which is responsible for all API deliveries (small molecules, drug-linkers and ADCs) to support pre-clinical and clinical studies, and drug product development activities. The pilot plant is also responsible for producing API primary stability batches, demonstrating the commercial process and control strategy, and generating the process knowledge and experience to enable a smooth Tech Transfer to commercial sites. Provide strategic leadership to all functions in the Pilot Plant for successful execution of pipeline deliverables, talent development and to drive efficiency and sustainability. Responsibilities: Ensure manufacturing of API clinical supplies in compliance with cGMP and AbbVie Quality and Regulatory standards, and consistent with project timelines. Lead the Pilot Plant Operations (manufacturing and materials management), Technical Operations and Engineering organizations to ensure successful execution of pipeline deliverables. Work collaboratively with partner functions, including Process R&D scientific organizations, QA and EHS to align on priorities and timelines, and to ensure safety and regulatory compliance. Ensure the development of strategies that drive technical excellence and innovation to improve future capabilities and productivity of the Pilot Plant and Process R&D. Responsible for leadership and technical development of employees within the organization to develop successful future leaders. Create a culture of empowerment that drives collaboration, engagement and accountability in the organization. Lead the talent management process to ensure employee development and effective succession planning. Actively drive performance excellence. Ensure projects and operating costs are managed within the approved capital and expense budgets for the pilot plant. Build strong relationships with internal and external partners, including drug product clinical manufacturing, TPMs and AbbVie commercial manufacturing sites. Benchmark with industry peers and implement strategies, new technologies and best practices to enable the pipeline, enhance efficiency and drive long term success. Champion innovative approaches and enabling technologies (flow chemistry, PAT, etc.) that have potential to deliver impactful solutions for API processes. Identify strategies to optimize allocation of key resources such as budget, capital, facilities and/or personnel to meet goals and to give AbbVie a competitive advantage. Qualifications: PhD in Chemical Engineering or a related discipline and 15 years of experience in the Pharmaceutical Industry, or Bachelor's/ Master's degree and 20 years of experience Demonstrated capability in leading large organizations Strong experience in API manufacturing operations Demonstrated capability to solve critical business and scientific problems Demonstrated ability to grow the capabilities of an organization and develop people into future leaders Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: biomedical, cytometry, drug, food scientist, histotechnologist, metabolism, nephrology, pharmacology, vaccine, virus

Associate Research Technician, In Vivo Biology (Vivarium) - San Francisco

newabout 15 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica, Venclexta, and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position is based at Stemcentrx, AbbVie's South San Francisco, CA location. AbbVie Stemcentrx is looking to hire a highly motivated team player who will join the team that supports early stage research and development. The qualified candidate must have strong interpersonal and communication skills, have a strong commitment to providing research support, and dedicated to providing humane animal care in accordance with the animal welfare regulations and local regulations of the IACUC. The candidate must be very reliable, be able to work independently or in a group setting that is dynamic and fast paced, be very focused and attentive to details and be able to provide high quality and consistent results.Key Responsibilities Includes: Supporting discovery research by ensuring the highest quality of animal care / husbandry and facility management. Husbandry work includes daily recording of room environments, daily animal health checks and reports, weekly cage changes, stocking of supplies and supporting in Vivo research staff. Must be willing to work weekends and holidays on a rotational basis, be able to lift 50 pounds, be willing to stand for long periods of time and be flexible in working longer hours. A.S. Degree in Biology or related discipline Minimum 1-3 years of directly related experience. AALAS certification is preferred but not required Ability to multitask and meet deadlines in a fast paced environment Ability to perform occasional physical labor involving lifting weight up to 50 pounds Willing to split weekend and holidays with peers on a rotational basis Excellent verbal and written communications skills Motivated to excel, learn, attentive to details Efficient in working alone or in a group environment. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: aseptic, bacteria, bio, bioengineering, biology, biostatistics, biotechnology, genome, immunobioengineering, virus

Scientist I/II, Protein Analytical Chemistry, CMC Biologics, Oncology Early Development - Redwood City

newabout 15 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica , Venclexta , and Empliciti and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus' and CAR-T cells. We are seeking a lab-based Protein Chemistry Scientist to join our Analytical Development team in developing and evaluating new drug discovery and existing clinical candidates. As part of our team, your major responsibilities will include analytical testing, method development and molecular characterization to support the development of antibodies, antibody variants and antibody drug conjugates (ADC). Scientist I: Bachelor's Degree in chemistry, biochemistry or a related field or equivalent education with typically 5 years of experience, or Master's Degree in chemistry, biochemistry or a related field or equivalent education with typically 2 years of experience. Scientist II: Bachelor's Degree in chemistry, biochemistry or a related field or equivalent education with typically 7 years of experience, or Master's Degree in chemistry, biochemistry or a related field or equivalent education with typically 5 years of experience. Knowledge of protein chemistry and monoclonal antibodies, hands-on use of HPLC, CE, and/or mass spectrometry instrumentation The ideal candidate will be hard-working, self-motivated, detail-oriented, highly organized and learn and adapt quickly. Excellent communication and interpersonal skills. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Associated topics: aseptic, bio, biotechnology, immunobioengineering, microbiology, pathophysiology, physical, protein, toxicologist, virus

Associate Director, User Experience

newabout 15 hours ago
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As the Associate Director, UX, you will nurture and scale a creative, design thinking culture ready to deliver Abbvie's next-generation digital solutions. This position requires a strong leader and connector with a consistent record of developing digital assets for global organizations with extensive R&D and B-to-C commercial functions. Do you love developing compelling visions and resource worthy plans that tackle meaningful problems? Do you love applying your deep practical knowledge of human centered design and UX approaches to help teams deliver delightful digital experiences? Do you love working collaboratively with diverse and agile technical teams? If so, you may be an excellent fit for this role at AbbVie. Join our mission to sustainably improve the lives of patients. This position reports to the Director of IT Innovation at AbbVie's global headquarters in Lake County, IL. Key Responsibilities: Help define and own the user experience practice for AbbVie's enterprise IT function Build a practical design practice that appropriately pairs the right approaches with project size to achieve high quality outcomes at reasonable cost Form, lead, and influence complementary teams of internal and external resources to offer an enterprise scale UX practice and services Utilize your strong business insight, intuition, and presentation skills to keep key partners and division leadership well-informed of progress and impact Some intangibles we value (and hope you value too): We are intrinsically curious and not afraid to pursue new ideas that challenge status quo We value customer input and get solutions into their hands quickly, to learn from their wisdom and correct our mistakes We confidently convey what has worked well and what has not We possess the ideation and design skills needed to define the best paths forward prior to further development and investment Basic: A minimum of 10 years industry/consulting or academic experience is required. A highly relevant BA MS or MBA degree is preferred (Computer Science, Human Factors, Human Computer Interface Design). It is expected that you will have a significant track record of leadership and solutions. At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, sex (including pregnancy), sexual orientation, gender identity, disability, protected veteran status or any other legally protected characteristic Equal Opportunity Employer Minorities/Women/Veterans/Disabled

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Specialist, (EHS) Employee Health & Safety Staff

newabout 15 hours ago
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Assists in the development and implementation of strategic programs, plans, policies and procedures to protect all plant personnel, facilities and the environment. Interprets, communicates and implements programs, policies, and procedures to ensure compliance with all applicable EHS regulations, corporate standards and OHSAS 18001 (Occupational Health & Safety Management System). Implement EHS programs and initiatives including, but not limited to: Hazard identification/risk assessment and planning/implementation of controls, High hazard control (Lockout Tagout, confined space, work permits, overhead hoists, machine guarding, electrical safety, fall protection, powered industrial trucks), Ergonomic job safety analysis, Contractor/construction EHS management, Industrial hygiene, Chemical safety/hazard communication, Emergency preparedness and response. Injury investigations to determine root cause and analysis and reporting of leading and lagging safety performance indicators to drive corrective actions. Develops and delivers EHS training on a wide variety of general safety topics such as hazard communication, contractor safety, emergency response and various physical safety programs. BS in safety, environmental, industrial hygiene, health physics, biological science, or related sciences. Minimum of 3 years experience in safety, environmental, industrial hygiene, health physics, or biological safety in the pharmaceutical manufacturing or R&D environment. Professional certifications in EHS preferred. Working experience in implementing EHS regulations, conducting incident investigations, interacting with regulatory agencies and external organizations and managing cross functional teams Development of practical, applicable standards and/or policies that meet business objectives. Technical expertise in the EHS functions as well as technical writing and business communications. Ability to actively listen, build and maintain effective working relationships with internal/ external colleagues and stakeholders, and resolve conflict. Ability to successfully manage project and programs. Ability to provide clear, concise, and effective verbal communications and well-developed written communication and presentation skills Ability to plan, organize, delegate, and follow-up on work flow in a team environment to meet departmental goals and objectives Well organized and have excellent attention to detail and thoroughness Proven ability to use email, Microsoft Word, Excel and Power Point and databases Equal Opportunity Employer Minorities/Women/Veterans/Disabled

jobs byAdzuna

Scientist I, Pharmacology

newabout 15 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica®, Venclexta™, and Empliciti™ and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. AbbVie is also expanding their expertise through partnering with companies leading the way in emerging biologic technologies including oncolytic virus' and CAR-T cells. This position is based at AbbVie in the Redwood City, CA location. We are looking for a highly motivated laboratory scientist to develop and evaluate biomarker and diagnostic strategies in support of the discovery, development and commercialization of novel therapies in immunology and immune oncology. The scientist will be responsible for assisting in the design and in performing complex laboratory investigations involving primary cell culture and Flow Cytometry (FACS) to identify biomarkers of efficacy/safety of development stage. While performing the duties the experience will provide a foundation in the discovery, characterization, clinical validation and utilization of innovative biomarkers and potential diagnostics in the drug development setting. The scientist would be expected to work collaboratively, under the supervision of experienced biomarker scientists. Core Job Responsibilities: The scientist will perform experiments involving use of animal blood, staining with fluorescently labeled antibodies and FACS. Independent laboratory investigations by the scientist will directly support the development the validation of clinically applicable biomarker assays (including pharmacodynamic, predictive, prognostic, safety and other biomarkers). The scientist must demonstrate proficiency analyzing and critiquing results, trouble-shooting experiments, drafting experimental protocols while designing, implementing and overseeing biomarker and data analysis The scientist must understand and adhere to corporate standards regarding code of conduct or operating procedures and maintain accurate records according to AbbVie policies. Bachelor's Degree Chemistry, Biology, or related field or equivalent education with typically 5 years of experience, or Master's Degree or equivalent education with typically two years of experience. Ability to learn and share knowledge with colleagues. Good oral and written communication skills. Actions demonstrate that group/project success benefit everyone. Demonstrated ability to work independently when generating precise, reliable, reproducible laboratory results. Ability to follow operating procedures accurately and, when appropriate, optimize procedures to enhance productivity and efficiency. Equal Opportunity Employer Minorities/Women/Veterans/Disabled

jobs byAdzuna

Senior Scientist I/II, Immuno-Oncology

newabout 15 hours ago
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Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica®, Venclexta™, and Empliciti™ - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position will be based at AbbVie Biotherapeutics (ABR), AbbVie's Center of Innovation in Oncology Research and Development, located in Redwood City, CA. ABR R&D efforts focus on two key areas: Immuno-Oncology (I-O): developing therapeutics that activate the immune system to recognize and eliminate cancer cells Antibody drug conjugates (ADCs); antibodies conjugated to potent toxins for directed delivery to cancerous cells while sparing healthy tissues. ABR employs approximately 160 individuals in the San Francisco Bay Area. Its size and entrepreneurial work force allows for effective cross-functional collaboration, agility, and rapid decision making. We are seeking a highly motivated individual to join AbbVie's rapidly expanding Immuno-Oncology group. The successful candidate will have expertise in T cell biology as well as cellular-based/chimeric T cell receptor-based therapeutics. This individual should have deep technical experience in immunology and oncology research with preferred experience in T cell biology including T cell receptors and peptide MHC antigens. This individual will be responsible for generating antigen-specific T cell clones, identifying and characterizing T cell receptors and engineering soluble T cell receptor-based therapeutics. This person will ensure scientific excellence, quality and completeness of key platform initiatives. The successful candidate will collaborate in a multidisciplinary research team in an exciting, fast-paced discovery-oriented environment. Ph.D. in Immunology or related major with typically 0-4 years (Senior Scientist I) or 4 years (Senior Scientist II) of experience. Preference for some industry experience Demonstrated excellence and productivity in independent research. Extensive knowledge of T cell biology research. Excellent written and verbal communication skills are essential. Level commensurate with experience Practical experience in primary cell culture, T cell based assays, and with molecular biology techniques is required. Skills include, but not limited to: flow cytometry (FACs), PCR, qPCR, ELISA, Luminex, retroviral/lentiviral based transduction systems, T cell clone generation. Highly developed written and communication skills, and the ability to work in a highly collaborative team setting is essential. Equal Opportunity Employer Minorities/Women/Veterans/Disabled

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2019 Experiential Internship (Graduate Level) - Process R&D, Scientist Intern

newabout 15 hours ago
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The AbbVie Experiential Internship Program As an AbbVie Experiential Intern, you'll participate in a paid, ten to twelve-week summer program that is focused on providing students with robust projects throughout the summer. As an intern, you will be located at our corporate headquarters in north suburban Chicago, with housing and shuttle services for eligible students. Department Overview - Process Research and Development AbbVie's Drug Substance Manufacturing Process Research and Development (PR&D) invents chemical processes and prepares active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies and drug product development for AbbVie's pre-clinical and clinical drug pipeline. PR&D scientists create valuable intellectual property through composition of matter, chemical processes, and technologies resulting in cost effective commercial manufacturing processes. PR&D also develops supply chain for APIs, and prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content. Assignment Details The summer intern will collaborate with organic chemists in AbbVie's Drug Substance Manufacturing Process R&D group to investigate the mechanism of a heterocycle forming organic reaction of relevance to the pharmaceutical industry. The goal is to prepare key heterocycle precursors by multi-step synthesis and conduct mechanistic experiments with these precursors. The intern will, with moderate supervision, design and conduct organic synthesis experiments, including reaction set up, work up, purification and final product characterization and analysis. In collaboration with AbbVie Chemists, the intern will also interpret the data acquired during mechanistic studies. A strong candidate will be proficient at designing practical synthetic routes, searching the relevant chemical literature to identify reaction conditions and familiar with fundamental physical organic chemistry and organic reaction mechanisms. Experience with modern analytical techniques of relevance to organic synthesis is required (e.g. 1H and 13C NMR analysis, GC, LCMS, GC/MS, HPLC). Basic: Completed at least one year of college education before beginning internship Must be enrolled in school the semester following your internship Graduate Level Student with degree/skills related to Synthetic organic chemistry Minimum Cumulative GPA: 3.0/4.0 Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship (students on an F1 visa with CPT can be accommodated). At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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Clinical Research Associate, Oncology - Salt Lake City, UT - AbbVie

new1 day ago
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…Monitors activities conducted by clinical investigative sites as they relate to AbbVie clinical studies to ensure successful execution of the protocol. Ensures

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Sr. Medical Science Liaison - Dermatology Atlanta - AbbVie

new1 day ago
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…within assigned geography. Provides education relative to disease state and AbbVie products across the product lifecycle to healthcare providers and researchers.

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Senior Scientist III, Chemical Engineering - AbbVie

new1 day ago
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…to enable clinical trials, toxicology studies and drug product development for AbbVie 's pre-clinical and clinical drug pipeline. In addition to working with small

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Scientist II/ Senior Scientist I, Virology - AbbVie

new1 day ago
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…scientist with background in Virology, Immunology, and/or molecular biology to join the AbbVie Infectious Disease team in North Chicago, IL. We are looking for a

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Senior Scientist, Process R&D Scientific Affairs - AbbVie

new2 days ago
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…is a member of the drug substance development teams that advance AbbVie 's small molecule and antibody drug conjugate pipelines. This non-laboratory position is

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Senior Director, Corporate Strategy Group - AbbVie

new2 days ago
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…perspective across all aspects of pharmaceutical R&D and commercial areas. At AbbVie , we value bringing together individuals from diverse backgrounds to develop new

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Manager, Statistics (Clinical) - AbbVie

4 days ago
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…and understanding of drug development in the regulated environment preferred. At AbbVie , we value bringing together individuals from diverse backgrounds to develop

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Scientist II/Sr. Scientist/Principal Scientist, Immunology

5 days ago
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Scientist II/Sr. Scientist/Principal Scientist, Immunology About Morphic Therapeutic Morphic ... Abbvie and Janssen that include >$100M upfront with future milestones. Integrins are involved in ...

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Associate Scientist I, DMPK

8 days ago
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AbbVie is seeking a highly motivated Associate Scientist to join our Drug Metabolism and Pharmacokinetics team in North Chicago. In this exciting role, you will be expected contribute to the success ...

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Quality Assurance Specialist

17 days ago
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... AbbVie functional areas and regulatory agencies. Qualifications: * Knowledge of global regulatory ... Preferred degree in technology or scientific background (MLT, LPN, RN). * 0-3 years' work ...

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Associate Scientist II, Bioanalysis and Biotransformation

22 days ago
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The Bioanalysis and Biotransformation Department at AbbVie has an opening for an Associate Scientist II position in North Chicago, IL. The successful candidate will be responsible for method ...

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